???: ?????????SPA?????????
???实名认证激活?手机卡哪里购买【+⋁:３０９6０９０4３】已经实名制认证激活的.不用实名制认证激活的.不需要实名制认证激活免实名制手机卡电话卡《⋁》【３０９6０９０4３】移动联通电信广电不记名手机卡匿名电话卡出售购买买卖交易平台??:??????3???? ???????
【咨询⋁;３０９6０９０4３】
“??,???????”?????,???????(??)?????,????????????
“?????,????????????????,???????,????????????,????????????????????????”???????????????????????????,??????????????????????“??????,??????????,??????,????,????????,????????????”???????????????????,?????????,??????,?????????,????????????,????????????
? “??????”?“???”??,?????????????,??????????????,??????«???????»?“?????,????????????,?????????????????,??,????????,?‘??’??????”
????????
???????????????,??????,???????????,??????????????????????,????????,???????40%??,?70%?????????,?????2-3???????,?????????????
?????????????????,???????????,???????????????,?????????????,???????????????BRCA????,????????????????????????,??????????????1.5%,?BRCA1??????????59%,BRCA2????16.5%???,?????,????????????BRCA????????????,???????????B??????????,«????????????????(2021??)»???,??????????,???????????,?????BRCA??????????????
“????????????????????,???????????????????,??????????”?????,????????????,?????????????,?????????,?????????,??????B?,???CT,?????????????
??+??+????,????????
“??????”????????????????????
?????????????,??????????“??????,?????????,??????????,????????,?????????,??????,?????????”?????????????????,??????????“??”????,????????????????????????,???????????????????,???????????????????,????????????
“??????????????,??????,????????”??????,??????,???????????,???????,??????????“???”???,?????????????,????????????????????,?????????,?????????,????????????????,?????????????
“??,???????????,??????,????????????????????????????????”?????,“??????PARP??????????????????,?????????????,????????????????”
????,????????
??,????????????8?,??????????,?????????“????”,??????????????“????”?“?????”????
?????,??????????????????,???????????????????????????????????????????BRCA?HRD???
“???????,?20%?BRCA????,???????????????PARP?????????”??????,“????????,HRD???????????????????,????????????50%,???????????68.7%?????PARP????????????????”
????PAOLA-1???????????,??PARP?????????????,HRD????????????5????????65.5%,?????????????????????
“??????????????????,??????,???????????????,???????????,???????”?????,“???‘?????????’,???????‘????????’,???????????,????????????,??????????????,??????‘???????’?”
???